Salivary metabolite profiling distinguishes patients with oral cavity squamous cell carcinoma from normal controls
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چکیده
منابع مشابه
Salivary Antioxidant Level in Oral Squamous Cell Carcinoma
Background: Oral cancer is among the 10 most common cancers worldwide with an increasing global incidence. Compromised antioxidant defense system plays a role in occurrence of cancer. This study evaluated the salivary antioxidant level of oral cancer patients compared to a control group. Patients and Methods: This case-control study was conducted on 22 oral squamous cell carcinoma patients pre...
متن کاملSaliva proteome profiling reveals potential salivary biomarkers for detection of oral cavity squamous cell carcinoma.
Oral cavity squamous cell carcinoma (OSCC), which is frequently associated with poor prognosis and mortality, is a leading cause of cancer-related death worldwide. Discovery of body fluid accessible biomarkers is needed to improve OSCC screening. To this end, we profiled proteomes of saliva from the healthy volunteers, the individuals with oral potentially malignant disorders (OPMD), and the OS...
متن کاملSalivary analytes in patients with oral squamous cell carcinoma.
Literature data indicates that measurement of certain salivary constituents might serve as a useful diagnostic/prognostic tool in the patients with oral squamous cell carcinoma (OSCC). In 24 patients with OSCC (60 +/- 2.5 yrs) and in 24 controls (24 +/- 3.7 yrs) we have determined levels of salivary magnesium, calcium, copper, chloride, phosphate, potassium, sodium, total proteins and amylase. ...
متن کاملComparison of the Concentration of Salivary IL-8 in Patients with Oral Squamous Cell Carcinoma and Healthy Subjects
Background and aim: oral cancer is one of the most common cancers of the head and neck. Considering the high prevalence and mortality percentage of oral cancer and the significant advances in immunology and identification of different cytokines, the aim of the present study was to compare the concentration of IL8 in saliva of patients with oral squamous cell carcinoma (OSCC) and healthy subject...
متن کاملChanges in Salivary Antioxidants in Patients with Oral Squamous Cell Carcinoma: Systematic Review Study and Meta-Analysis
Background and Objective: Oral cancer is one of the 10 most common cancers in the world and its global outbreak is increasing. Saliva assessment is one of the non-invasive diagnostic methods for this cancer. The aim of the study was to achieve a comprehensive conclusion about changes in salivary antioxidants in patients with squamous cell carcinoma of the mouth (OSCC). Materials and Methods: I...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2018
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0204249